李岩 博士

副教授，硕士生导师（生物工程学硕、专硕）

●  出生年月

1983年12月

● 工作经历

2021.4至今：烟台大学，生命科学学院，副教授

2013.12-2021.3 中国科学院烟台海岸带研究所，助理研究员、副研究员

● 学习经历

2010.9-2013.12, 中国农业大学, 微生物学, 博士,

2007.9-2010.7, 云南大学, 微生物学, 硕士,

● 主讲课程

本科生课程：《微生物学》，《生物信息学》

研究生课程：《生物信息学》

● 研究方向

微生物资源开发应用，微生物组解析，合成微生物群落设计与应用，基因组生物信息学

● 教学、科研项目

1. 植物通过根际对话偏好性调控根际活跃固氮菌群的机制，国家自然科学基金面上项目，2026.01-2029.12，在研，主持

2. 提高果园土壤生产力和果实品质的绿色投入品研发及产业化，山东省重点研发计划，2024.09-2026.08，在研，主持

3. 提高果园土壤生产力和果实品质的绿色投入品研发及产业化，潍坊市科技计划，2024.09-2026.08，在研，主持

4. 苹果专用微生物菌剂及生物有机肥的研发、中试及产业化，企业委托横向项目，2024.07-2026.12，在研，主持

5. 葡萄叶际抗炭疽病微生物组解析及抗病群落构建，烟台市科技计划，2024.01-2026.12，在研，合作单位主持

6. 新型抗苹果炭疽病免疫增强型小肽的挖掘与作用机制研究，烟台市科技计划，2024.01-2026.12，在研，合作单位主持

7. 烟草关键性状的微生物组学研究，横向课题，2023.07-2025.12，在研，主持

8. 农田原位不同结瘤能力花生的固氮微生物组解析及极简固氮微生物组的人工构建，烟台大学学科带头人启动经费，2021.06-2026.05，在研，主持

9. 农田原位不同结瘤能力花生的固氮微生物组解析及极简固氮微生物组的人工构建，山东省自然科学基金面上项目，2022.01-2024.12，结题，主持

10. 功能微生物绿色转化菌渣研制有机肥技术研究及示范，河北省重点研发计划，2019.07-2021.12，结题，主持

11. 基于中药渣高值化应用的盐碱地专用微生物有机肥研制及产业化，吉林省与中科院科技合作高技术产业化资金项目，2019.01-2020.12，结题，主持

12. 盐碱地土壤改良菌剂及微生物有机肥研发，中科院烟台海岸带研究所前沿部署项目，2018.01-2019.12，结题，主持

13. 环境因子对花生根瘤菌遗传多样性和分布的影响机制，国家自然科学基金青年基金，2017.01-2019.12，结题，主持

14. 烟台近海养殖区脱硫微生态制剂的研制及应用，烟台市科技计划，2018.01-2019.12，结题，主持

15. 黄渤海海草共附生微生物驱动的硫循环通量及耦合转化机制，国家自然科学基金重大研究计划，结题，参加，第二位

16. LuxR solo调控因子Sla1在茎瘤固氮根瘤菌自生和菌植互作共生中的调控作用，国家自然科学基金青年科学基金，2019.01-2021.12，结题，参加，第二位

● 主要论文、专著及专利

第一或通讯作者论文

1. Wang Xiaohan, Chen Shujin, Zhang Xirui, Liang Bin, Li Xiulian, Li Yan*, Sun Chanchan*. Double-crosslinked pea protein isolation-sodium alginate composite microgels embedding Lactobacillus plantarum: effect of calcium chloride concentration. LWT. 2025, 222: 117670.

2. Li Juan, Yang Zhong De, Wang En Tao, Sun Li Qin*, Li Yan*. The effect of climate variables, soil characteristics, and peanut cultivars on the rhizobial bacteria community. Microorganisms. 2025; 13(4):926.

3. 郭亭妍, 连昭, 孙利芹, 李岩*. 莱州湾沉积物可培养硫氧化细菌多样性研究.微生物学杂志. 2025, 45 (2): 43-51.

4. Li Yan, Guo Tingyan, Sun Liqin, Wang En-Tao, Young J. Peter W., Tian Chang-Fu. Phylogenomic analyses and reclassification of the Mesorhizobium complex: proposal for 9 novel genera and reclassification of 15 species. BMC Genomics. 2024, 25 (1): 419.

5. Xu Yalong, Li Jingjing, Qiao Chan, Yang Jinchu, Li Juan, Zheng Xueao, Wang Chen, Cao Peijian, Li Yan*, Chen Qiansi*. Rhizosphere bacterial community is mainly determined by soil environmental factors, but the active bacterial diversity is mainly shaped by plant selection. BMC Microbiol. 2024, 24(1):450.

6. Zhang, Haikun, Cheng Manman, Li Yan^*, and Chen Wenhao^*. Quinoid redox mediators and their involvement in environmental pollution treatment. Water. 2023, 15(22): 3981.

7. Cheng Manman, Zhang Haikun, Li Yan^* and Chen Wenhao^*. Riboflavin secreted by Shewanella sp. FDL-2 facilitates its reduction of Se(iv) and Te(iv) by promoting electron transfer. RSC Adv, 2023,13: 34445-34454.

8. Xin Quandong, Chen Jufa, Mu Changkao, Wang Xinliang, Liu Wenjing, Jiang Tao^*, Li Yan*. Community composition, co-occurrence, and environmental drivers of bacterioplankton community in surface and 50 m water layers in the subarctic North Pacific. J Oceanol Limnol, 2023, 41: 2309-2323.

9. Han Kunming, Yan Li, Zhang Zhenpeng, Sun Liqin, Wang En Tao, Li Yan *. Comparative genome analysis of Sesbania cannabina-nodulating Rhizobium spp. revealing the symbiotic and transferrable characteristics of symbiosis plasmids. Microb Genomics, 2023, 9: 001004.

10. 黎萍, 高新星, 韩昆明, 孙利芹, 李岩*. 花生根际微生物的分离及高效功能菌株筛选. 微生物学通报, 2023, 50(10): 4433−4447.

11. Li Yan^*, Liu Guohua, Han Kunming, Sun Liqin, Gao Kangning, Liu Wei, Wang En Tao, Chen Wenhao. Distribution and biodiversity of rhizobia nodulating Chamaecrista mimosoides in the Shandong peninsula of China. Syst Appl Microbiol, 2022, 45(1), 126280.

12. Liu Guohua, Liu Xiaoling, Liu Wei, Gao Kangning, Chen Xiaoli, Wang En-Tao, Zhao Zhenjun^*, Du Wenxiao^*, Li Yan^*. Biodiversity and geographic distribution of rhizobia nodulating with Vigna minima. Front Microbiol, 2021, 12: 665839.

13. Zhang zhenpeng, Liu Wei, Shao Shuai, Wang En-Tao, Li Yan^*. Diverse genomic backgrounds Vs. highly conserved symbiotic genes in Sesbania-nodulating bacteria: shaping of the rhizobial community by host and soil properties. Microb Ecol, 2020, 80: 158-168.

14. Liu Wei^#, Li Yan^#, Bai Xue, Wu Haiguang, Bian Lanxing, Hu Xiaoke^*. LuxR-type regulator AclR1 of Azorhizobium caulinodans regulates cyclic di-GMP and numerous phenotypes in free-living and symbiotic states. Mol Plant Microbe In, 2020, 33(3): 528-538.

15. Shao Shuai, Chen Mingna, Liu Wei, Hu Xiaoke, Wang En-Tao, Yu Shanlin*, Li Yan*. Long-term monoculture reduces the symbiotic rhizobial biodiversity of peanut. Syst Appl Microbiol. 2020, 43: 126101.

16. Wu Fanlin^#, Li Yan^#, Tian Wei, Sun Yadong, Chen Feiyan, Zhang Yurou, Zhai Yuxuan, Zhang Jing, Su Hongyan, Wang Lei. A novel dark septate fungal endophyte positively affected blueberry growth and changed the expression of plant genes involved in phytohormone and flavonoid biosynthesis. Tree Physiol. 2020, 40(8): 1080-1094.

17. 邵帅, 王玲玲, 林剑, 徐世艾, 李岩^*. 产纤维素酶真菌分离及高效菌株筛选. 河南农业科学, 2020, 49(4): 55-61.

18. Zhang Zhenpeng#, Li Yan#, Pan Xiaohan et al. Aeschynomene indica-nodulating rhizobia lacking nod factor synthesis genes: diversity and evolution in Shandong Peninsula, China. Appl Environ Microbiol, 2019, 85(22), e00782-19.

19. Li Yan, Zhang Zhenpeng, Xu Zhenxing, et al. Jeotgalibacillus proteolyticus sp. nov., a protease-producing bacterium isolated from ocean sediments. Int J Syst Evol Microbiol. 2018, 68: 3790-3795.

20. Li Yan, Wu Chaoya, Zhou Mingyang, et al. Diversity of cultivable protease-producing bacteria in Laizhou Bay sediments, Bohai Sea, China. Front Microbiol. 2017, 8: 405.

21. Li Yan, Zhou Mingyang, Wang Fengqing, et al. Photobacterium proteolyticum sp. nov. a protease producing bacterium isolated from ocean sediments of Laizhou Bay. Int J Syst Evol Microbiol. 2017, 67(6):1835-1840.

22. Li Yan, Li Xiangyue, Liu Yajing, et al. Genetic diversity and community structure of rhizobia nodulating with Sesbania cannabina in the saline-alkaline soils. Syst Appl Microbiol. 2016, 39(3): 195–202.

23. Li Yan, Wang En-Tao, Yajing Liu, et al. Rhizobium anhuiense as the predominant microsymbionts of Lathyrus maritimus along the Shandong Peninsula seashore line. Syst Appl Microbiol. 2016, 39 (6): 384–390.

24. Li Yan, Yan Jun, Yu Bing, et al. Ensifer alkalisoli sp. nov., isolated from root nodules of Sesbania cannabina grown in saline-alkaline soils. Int J Syst Evol Microbiol. 2016, 66:5294-5300.

25. Li Yan, Tian Changfu *, Chen Wenfeng, Wang Lei, Sui Xinhua, Chen Wenxin. High-resolution transcriptomic analyses of Sinorhizobium sp. NGR234 bacteroids in determinate nodules of Vigna unguiculata and indeterminate nodules of Leucaena leucocephala. PLoS ONE. 2013, 8(8): e70531.

26. 李岩，董雷，王磊，方福瑾，何敏，曹中莹，梁媛，唐蜀昆，李文均*. 极端耐盐放线菌白色普氏菌YIM 90005^T 四氢嘧啶及5-羟基四氢嘧啶合成相关基因的克隆. 微生物学报. 2011, 51: 603-608.

27. Wang Jian^#, Li Yan^#, Bian Jiang, Tang Shukun, Ren Biao, Chen Ming, Zhi Xiaoyang, Zhang Yuqin, Li Wenjun* and Zhang Lixin*. Prauserella marina sp. nov., isolated from ocean sediment of the South China Sea. Int J Syst Evol Microbiol. 2010, 60: 985-989.

28. Liu Zui^#, Li Yan^#, Zheng Liuqiang, Huang Yaojian* and Li Wenjun*. Saccharomonospora marina sp. nov., isolated from an ocean sediment in the East China Sea. Int J Syst Evol Microbiol. 2010, 60: 1854-1857.

29. Li Yan, Tang Shukun, Chen Yiguang, Wu Jinyuan, Zhi Xiaoyang, Zhang Yuqin and Li Wenjun *. Prauserella salsuginis sp. nov., Prauserella flava sp. nov., Prauserella aidingensis sp. nov. and Prauserella sediminis sp. nov., isolated from a salt lake. Int J Syst Evol Microbiol. 2009, 59: 2923-2928.

30. Bian Jiang, Li Yan^#, Wang Jian, Song Fuhang, Liu Mei, Dai Huanqin, Ren Biao, Gao Hong, Hu Xinling, Liu Zhiheng, Li Wenjun* and Zhang Lixin. Amycolatopsis marina sp. nov., a novel actinomycete isolated from an ocean sediment. Int J Syst Evol Microbiol. 2009, 59: 477-481.

参与论文

1. Fang Suyun, Min Jun, Zhang Haikun, Li Yan, Lin Xingyue, Hu Xiaoke. Shewanella mytili sp. nov., a novel bacterial species isolated from the intestinal tract of Mytilus edulis in the South China Sea. Anton Leeuw. 2025, 118, 132.

2. Fang Suyun, Lin Xingyue, Min Jun, Li Yan, Chang Kim Lee, Hu Xiaoke. Pseudoalteromonas pernae sp. nov., a novel bacterium with antimicrobial potential isolated from the intestinal tract of mussel genus Perna (Bivalvia: Mytilidae). Int J Syst Evol microbiol. 2025, 75(8).

3. Liu, Xiao, Zhao Wentao, Li Yan, Sun Zhongliang, Lu Chang, Sun Liqin. Genome analysis of a polysaccharide-degrading bacterium Microbulbifer sp. HZ11 and degradation of alginate. Mar Drugs. 2024, 22(12): 569.

4. Rivera Ortuña Flor N., Guevara-Luna Joseph, Yan Jun, Lopez Amezcua Eloisa, Arroyo-Herrera Ivan, Li Yan, Vásquez-Murrieta Maria Soledad, Rojas Arellano Danae, Wang En Tao. Rhizobium hidalgonense and Rhizobium redzepovicii as faba bean (Vicia faba L.) microsymbionts in Mexican soils. Arch Microbiol. 2024, 206: 281.

5. Min Jun, Fang Suyun, Peng Jian, Lv Xin, Xu Lingxue, Li Yan, Hu Xiaoke^*. Microbial detoxification of 2,4,6-tribromophenol via a novel process with consecutive oxidative and hydrolytic debromination: Biochemical, genetic and evolutionary characterization. Environ Res. 2022, 205: 112494.

6. Liu Wei, Bai Xue, Li Yan, Min Jun, Kong Yachao, Hu Xiaoke. CheY1 and CheY2 of Azorhizobium caulinodans ORS571 regulate chemotaxis and competitive colonization with the host plant. Appl Environ Microbiol, 2020, 86: e00599-20.

7. Yang Lingling, Jiang Zhao, Li Yan, Wang En-Tao, Zhi Xiaoyang. Plasmids related to the symbiotic nitrogen fixation are not only cooperated functionally but also may have evolved over a time span in family Rhizobiaceae. Genome Biol Evol. 2020, 12(11):2002-2014.

8. Sun Yanwei, Li Yan, Hu Yue, Chen Wenxin, Tian Changfu^*. Coordinated regulation of size and number of PHB granules by core and accessory phasins in the facultative microsymbiont Sinorhizobium fredii NGR234. Appl Environ Microbiol, 2019, 85(19): e00717-19.

9. Zhao Huilin, Zhang Cong, Wu Yulong, Zhang Xiying, Rong Qianyu, Xu Zheng, Ding Yunfei, Li Yan, Du Zhenzhen, Zhou Xiuzhi, Li Boqing, Ji Xiaofei. Thalassorhabdomicrobium marinisediminis gen. nov., sp. nov., a member of the family Hyphomonadaceae isolated from the Bohai Sea. Int J Syst Evol microbiol, 2019, 69(6): 1794-1799.

10. Liu Wei, Shen Rimin, Dang Xiaoxiao, Liu Xiaolin, Sui Fu, Li Yan, Zhang Zhenpeng, Gladys Alexandre, Claudine Elmerich, Xie Zhihong^*. A chemotaxis-like pathway of Azorhizobium caulinodans controls flagella-driven motility, which regulates biofilm formation, exopolysaccharide biosynthesis, and competitive nodulation. Mol Plant Microb In, 2018, 31 (7): 737-749.

11. Yan Jun, LiYan, Yan Hui, et al. Agrobacterium salinitolerans sp. nov., a saline–alkaline-tolerant bacterium isolated from root nodule of Sesbania cannabina. Int J Syst Evol Microbiol. 2017, 67: 1906-1911.

12. Yan Jun, Li Yan, Han Xiao-zeng, Chen Wenfeng, Zou Wenxiu, Li Meng^*. Agrobacterium deltaense sp. nov., an endophytic bacteria isolated from nodule of Sesbania cannabina. Arch Microbiol. 2017, 7: 1003–1009.

13. Liu Wei, Yang Jinbao, Sun Yu, Liu Xiaolin, Li Yan, Zhang Zhenpeng. Azorhizobium caulinodans transmembrane chemoreceptor TlpA1 involved in host colonization and nodulation on roots and systems. Front Microbiol. 2017, 8: 1327.

14. Jiao Jian, Wu Lijuan, Zhang Biliang, Hu Yue, Li Yan, Zhang Xingxing, Guo Huijuan, Liu Lixue, Chen Wenxin, Zhang Ziding, Tian Changfu^*. MucR is required for transcriptional activation of conserved ion transporters to support nitrogen fixation of Sinorhizobium fredii in soybean nodules. Mol Plant Microb In, 2016, 29(5): 352-361.

15. 吴海龙，李岩，陈明娜，刘卫，任承钢，杨金保，禹山林^*. 花生根瘤菌遗传多样性及高效固氮菌株的筛选[J]. 花生学报, 2016, 45(2): 1-8.

16. Yan Jun, Han Xiaozeng, Ji Zhaojun, Li Yan, Wang Entao, Chen Wenfeng. Abundance and diversity of soybean-nodulating rhizobia in black soil are impacted by land use and crop management. Appl Environ Microbiol, 2014, 80(17): 5394-5402.

17. Li Mao, Li Yán, Chen Wen-Feng*, Sui Xin-Hua, Li Ying, Li Yàn, Wang En-Tao, Chen Wen-Xin. Genetic diversity, community structure and distribution of rhizobia in the root nodules of Caragana spp. from arid and semi-arid alkaline deserts, in the north of China. Syst Appl Microbiol. 2012, 35: 239–245.

18. Jun-Jie Zhang, Tian-Yan Liu, Wen-Feng Chen*, En-Tao Wang, Xin-Hua Sui, Xiao- Xia Zhang, Yán Li, Yàn Li, and Wen-Xin Chen. Mesorhizobium muleiense sp. nov., nodulating with Cicer arietinum L. in Xinjiang, China. Int J Syst Evol Microbiol. 2012, 62, 2737–2742

19. Zhi-Chun Wang, Jing-Liang Xu, Yan Li, Kun Wang, Yang-Yang Wang, Qing Hong, Wen-Jun Li* and Shun-Peng Li*. Rhodococcus jialingiae sp. nov., a novel actinobacterium isolated from sludge of a carbendazim wastewater treatment facility. Int J Syst Evol Microbiol. 2010, 60: 378-381.

20. Man Cai, Shu-Kun Tang, Yi-Guang Chen, Yan Li, Yu-Qin Zhang and Wen-Jun Li*. Streptomonospora amylolytica sp. nov. and Streptomonospora flavalba sp. nov., two novel halophilic actinomycetes isolated from a salt lake. Int. J. Syst. Evol. Microbiol. 2009, 59: 2471-2475.

21. Xin-Qing Zhao, Wen-Jun Li, Wen-Ce Jiao, Yan Li, Wen-Jie Yuan, Yu-Qin Zhang, Hans-Peter Klenk, Joo-Won Suh, and Feng-Wu Bai*. Streptomyces xinghaiensis sp. nov., a new actinomycete derived from marine sediment sample in Xinghai Bay, Dalian, China. Int J Syst Evol Microbiol. 2009, 59: 2870-2874.

22. 吴晋元，职晓阳，李岩，关统伟，唐蜀昆，徐丽华，李文均*. 云南江城和黑井盐矿沉积物未培养放线菌多样性比较. 微生物学通报, 2008, 35: 1550-1555.

专著

胡晓珂，王鹏等 海岸带功能微生物及其应用，科学出版社，北京. 2021.03. 参编（副主编）

专利

1. 李岩, 王一飞, 孙利芹, 李娟, 张帆. 花生根际非共生固氮菌及其应用. 发明专利, 申请号：2025105462753.

2. 李岩，李项岳，任承钢，刘卫，吴海龙，姜南. 一种根瘤菌及其应用，ZL 2015 1 0585141.9，中国，发明专利, 2019.03.01.

2. 李岩，王玲玲，韩京龙，常大勇，刘卫，任承钢. 产纤维素酶细菌及应用，ZL 2016 1 0378968.7，中国，发明专利，2019.04.09

3.李岩, 王玲玲, 韩京龙, 刘卫, 任承钢. 产纤维素酶放线菌及应用. ZL 2016 1 0114479.0，中国，发明专利，2019.08.09

● 荣誉奖励

海洋功能微生物酶资源的开发与转化技术研究，海洋科学技术奖，自然资源部，二等奖，参加 9/10

中国科学院烟台海岸带研究所2018年度优秀个人

● 学术兼职

国家自然科学基金函评专家；

Frontiers in Marine Science, Review editor；

Frontiers in Microbiology, Associate editor；

微生物学杂志审稿人，Appl Environ Microbiol、Microbial Ecolgy等多个英文专业杂志审稿人；

亚洲可持续农业PGPR协会，终身荣誉会员.

● 联系方式

通信地址：山东省烟台市莱山区清泉路30号，烟台大学生命科学学院

电邮：liyan0709@hotmail.com