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于娟  博士/副教授

出生年月

1990年8月

工作经历

202207-至今:烟台大学,生命科学学院,副教授

学习经历

201907-202207月:天津科技大学轻工技术与工程科研流动站制糖工程,博士

201409-201906月:天津科技大学食品科学硕博连读

201009-201407月:青岛农业大学,食品科学与工程,本科生

主讲课程

暂无

研究方向

主要从事天然产物结构表征和生物活性方面的研究,研究方向包括:

1. 功能性食品及其生物活性机理研究

2. 以多糖为基础的纳米材料的制备及其抗肿瘤机制研究

3. 生物活性多糖的分离、结构解析及其与生物活性构效关系研究

教学、科研项目

 

[1] 菊粉型果聚糖/β-乳球蛋白复合体系的构建机制及其对ω-3 PUFAs的靶向控释机理研究烟台大学青年博士科研基金项目,20万元,1/12022-2027,在研,主持。

[2] 铁皮石斛降脂速溶茶的开发及体内降脂机制研究(2100820087),横向项目,3.0万元,结题,主持。

[3] 药食同源植物多糖优化、结构及其功能活性研究(2000820058),横向项目,1.5万,结题,主持。

[4] 抗氧化功能食品开发(2000820045),横向项目,30万,在研,参与。

[5] 基于颗粒与聚合物界面的纤维素与肌原纤维蛋白相互作用机制及对肉凝胶质构和流变学性质的影响研究,国家自然科学基金面上项目,58万,在研,参与。

[6] 亚硒酸化β-乳球蛋白真空氧化还原导入机制及其抗衰老机理研究,国家自然科学基金,82万元,结题,参与。

[7] 食品专用蛋白基料制备关键技术研究与开发,国家高技术研究计划(863),776万元,结题,参与。

主要论文

[1] Yu Juan, Dong Xiao-dan, Jiao Jian-shuang, Yu Sha-sha, Ji Hai-yu*, Liu An-jun*, Chen Ye*. Extraction, purification, and biological activities in vivo of a novel fructose-rich polysaccharide from Codonopsis pilosula [J]. Industrial Crops & Products, 2022, 176: 114309. (SCI收录期刊, 1)

[2] Yu Juan, Dong Xiao-dan, Jiao Jian-shuang, Yu Sha-sha, Ji Hai-yu*, Liu An-jun*, Chen Ye. The inhibitory effects of selenium nanoparticles modified by fructose-enriched polysaccharide from Codonopsis pilosula on HepG2 cells [J]. Industrial Crops & Products, 2022, 176. 114335. (SCI收录期刊, 1)

[3] Yu Juan, Dong Xiao-dan, Jiao Jian-shuang, Ji Hai-yu*, Liu An-jun*. Antitumor and immunoregulatory activities of a novel polysaccharide from Astragalus membranaceus on S180 tumor-bearing mice [J]. International Journal of Biological Macromolecules, 2021, 189: 930-938. (SCI收录期刊, 1)

[4] Dong Xiao-dan, Liu Yi-ning, Zhao Yan, Liu An-jun*, Ji Hai-yu, Yu Juan*. Structural characterization of a water-soluble polysaccharide from Angelica dahurica and its antitumor activity in H22 tumor-bearing mice [J]. International Journal of Biological Macromolecules, 2021, 193: 219-227. (SCI收录期刊, 1)

[5] Yu Juan, Liu Chao, Ji Hai-yu*, Liu An-jun*. The caspases-dependent apoptosis of hepatoma cells induced by an acid-soluble polysaccharide from Grifola frondosa [J]. International Journal of Biological Macromolecules, 2020, 159: 364-372. (SCI收录期刊,2)

[6] Yu Juan, Ji Hai-yu*, Liu Chao, Liu An-jun*. The structural characteristics of an acid-soluble polysaccharide from Grifola frondosa and its antitumor effects on H22-bearing mice [J]. International Journal of Biological Macromolecules, 2020, 158: 1288-1298. (SCI收录期刊, 2)

[7] Dong Xiao-dan, Feng Ying-ying, Liu Yi-ning, Ji Hai-yu, Yu Sha-sha, Liu An-jun*, Yu Juan*. A novel polysaccharide from Castanea mollissima Blume: Preparation, characteristics and antitumor activities in vitro and in vivo [J]. Carbohydrate Polymers, 2020, 240: 116323. (SCI收录期刊, 1)

[8] Yu Sha-sha, Ji Hai-yu, Dong Xiao-dan, Liu An-jun*, Yu Juan*. FAS/FAS-L-mediated apoptosis and autophagy of SPC-A-1 cells induced by water-soluble polysaccharide from Polygala tenuifolia [J]. International Journal of Biological Macromolecules, 2020, 150: 449-458. (SCI收录期刊, 2)

[9] Yu Juan#, Ji Hai-yu#, Dong Xiao-dan, Feng Ying-ying, Liu An-jun*. Apoptosis of human gastric carcinoma MGC-803 cells induced by a novel Astragalus membranaceus polysaccharide via intrinsic mitochondrial pathways [J]. International Journal of Biological Macromolecules, 2019, 126: 811-819. (SCI收录期刊, 2)

[10] Yu Juan#, Ji Hai-yu#, Yang Zhi-zhi, Liu An-jun*. Relationship between structural properties and antitumor activity of Astragalus polysaccharides extracted with different temperatures [J]. International Journal of Biological Macromolecules, 2019, 124: 469-477. (SCI收录期刊, 2)

[11] Yu Juan#, Dong Xiao-dan#, Wang Ling-ling, Ji Hai-yu, Liu An-jun*. Antitumor effects of seleno-beta-lactoglobulin (Se-beta-Lg) against human gastric cancer MGC-803 cells [J]. European Journal of Pharmacology, 2019, 846: 128-130. (SCI收录期刊, 3)

[12] 于娟, 纪海玉, 白云, 孙苏军, 刘安军*. 红茶多酚对H22荷瘤小鼠的免疫调节和抗氧化作用 [J]. 中国食品学报, 2019, 19(10): 49-55. (EI收录)

[13] Yu Juan, Ji Hai-yu, Liu An-jun*. Alcohol-soluble polysaccharide from Astragalus membranaceus: Preparation, characteristics and antitumor activity [J]. International Journal of Biological Macromolecules, 2018, 118: 2057-2064. (SCI收录期刊, 2)

[14] Yu Juan, Ji Hai-yu, Liu An-jun*. Preliminary structural characteristics of polysaccharides from pomelo peels and their antitumor mechanism on S180 tumor-bearing mice [J]. Polymers (Basel), 2018, 10(4). (SCI收录期刊, 2)

[15] 于娟, 纪海玉, 王玉芳, 贾贺威, 刘安军*. 麒麟菜多糖体内抗肿瘤机理研究 [J]. 现代食品科技, 2017, 33(05): 14-19. (中文核心期刊)

荣誉奖励

 

1. 第一届全国博士后创新创业大赛--创业赛 银奖,2021

联系方式

通信地址:山东省烟台市莱山区清泉路30号,烟台大学生命科学学院

邮编:264005

Email:yj0805@ytu.edu.cn